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Gene expression profile of follicular thyroid tumors

✍ Scribed by M. Oczko-Wojciechowska; A. Kukulska; D. Lange; E. Chmielik; M. Kowalska; E. Gubala; A. Pfeifer; B. Jarzab


Book ID
119598611
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
89 KB
Volume
6
Category
Article
ISSN
1359-6349

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The PTEN (MMAC1/TEP1) tumor suppressor gene was recently isolated and mapped to human chromosome band 10q23. Homozygous deletions and mutations of PTEN were observed in cell lines and sporadic cancers of the breast, kidney, and central nervous system. Germline mutations in PTEN were recently found i