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Gene expression of flap endonuclease-1 during cell proliferation and differentiation

✍ Scribed by In-Sook Kim; Mun-Yong Lee; Il-Ha Lee; Soon-Lim Shin; Soo-Young Lee


Book ID
117350520
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
443 KB
Volume
1496
Category
Article
ISSN
0167-4889

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The products of proliferating cell nuclear antigen (PCNA) and flap endonuclease (FEN1) genes are multifunctional proteins that are involved in DNA replication and damage repair. Yeast models suggest association of mutant forms of PCNA and FEN1 with genomic instability. In our study, we have determin

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