Gene expression and active virus replication in the liver after injection of duck hepatitis B virus DNA into the peripheral vein of ducklings
β Scribed by Masami Tagawa; Osamu Yokosuka; Fumio Imazeki; Masao Ohto; Masao Omata
- Book ID
- 118567275
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 943 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0168-8278
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## Abstract The integration of hepatitis B virus (HBV) DNA in the liver of chronic HBV carriers has been documented extensively. However, the status of the viral genome during acute infection has not been assessed conclusively. While HBV DNA sequences are detected often in serum, liver, and periphe
A method is described that enables the unequivocal detection of the integration of hepatitis B virus DNA (HBV-DNA) into the genomic DNA of the host cell, while at the same time the virus exhibits active replication. This detection was achieved by separating the low molecular weight replicating HBV-D
## VICENTE CARRENO The presence of hepatitis B virus DNA was studied in peripheral blood mononuclear cell samples from 259 HBsAg carriers (229 anti-hepatitis delta negative, 30 anti-hepatitis delta positive), 16 anti-HBc-positive HBsAg-negative patients and 30 patients without hepatitis B virus ma