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Gene expression analysis reveals HOX gene upregulation in trisomy 8 AML

✍ Scribed by Kok, C H; Brown, A L; Ekert, P G; D'Andrea, R J

Book ID
109887417
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
567 KB
Volume
24
Category
Article
ISSN
0887-6924

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Impact of trisomy 8 on expression of gen
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✍ Claudia Schoch; Alexander Kohlmann; Martin Dugas; Wolfgang Kern; Susanne Schnitt πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 English βš– 140 KB

## Abstract Trisomy 8 is the most frequently observed trisomy in acute myeloid leukemia (AML) occurring as a sole karyotype abnormality or in addition to other chromosome aberrations. It was the aim of this study to analyze the impact of trisomy 8 on the expression of genes located on chromosome 8