## Abstract Huntington's disease (HD) is a progressive neurodegenerative disorder caused by an expanded CAG repeat region in exon 1 of the HD gene. This mutation results in the presence of an abnormally long polyglutamine tract in the encoded protein, huntingtin (htt). A major question in this fiel
Gene Dysregulation in Huntington’s Disease: REST, MicroRNAs and Beyond
✍ Scribed by Rory Johnson; Noel J. Buckley
- Book ID
- 107568609
- Publisher
- Humana Press Inc
- Year
- 2009
- Tongue
- English
- Weight
- 503 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1535-1084
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## Abstract Disturbances of visual cognition, visuomotor performance, and visual memory have been described frequently in Huntington's disease (HD). Early stage visual abnormalities could contribute to these deficits. We evaluated visual processing in 20 control subjects who were non‐gene carriers
## Abstract Although the Unified Huntington's Disease Rating Scale (UHDRS) is widely used in the assessment of Huntington disease (HD), the ability of individual items to discriminate individual differences in motor or behavioral manifestations has not been extensively studied in HD gene expansion