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Gene Delivery by Aminofullerenes: Structural Requirements for Efficient Transfection

✍ Scribed by Hiroyuki Isobe; Waka Nakanishi; Naoki Tomita; Shigeki Jinno; Hiroto Okayama; Eiichi Nakamura


Book ID
112005115
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
296 KB
Volume
1
Category
Article
ISSN
1861-4728

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Novel cationic pentablock copolymers with poly(diethylamino ethyl methacrylate) blocks covalently attached to parent triblock Pluronic copolymers have been designed and developed as sustained release non-viral gene delivery vectors. These copolymers electrostatically condense plasmid DNA into nanost