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Gene cloning and heterologous expression of a serine protease from Streptomyces fradiae var.k11

โœ Scribed by Meng, Kun; Li, Jiang; Cao, Yanan; Shi, Pengjun; Wu, Bo; Han, Xiaoyu; Bai, Yingguo; Wu, Ningfeng; Yao, Bin


Book ID
115518741
Publisher
NRC Research Press
Year
2007
Tongue
French
Weight
160 KB
Volume
53
Category
Article
ISSN
0008-4166

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Cloning and expression of a tylosin resi
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A gene conferring high-level resistance to tylosin in Streptomyces lividans and Streptomyces griseofuscus was cloned from a tylosin-producing strain of Streptomyces fradiae. The tylosin-resistance (Tylr) gene (tlrA) was isolated on five overlapping DNA fragments which contained a common 2.6 Kb KpnI