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Gene Chip Analysis for Detection of Potential Tumor Suppressor Genes in Colorectal Cancer Cell Lines

✍ Scribed by Gock, Michael C. ;Koczan, Dirk ;Klar, Ernst ;Linnebacher, Michael

Book ID: 122146860
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 89 KB
Volume: 140
Category: Article
ISSN: 0016-5085
DOI: 10.1016/S0016-5085(11)64331-X

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## Abstract Loss of heterozygosity (LOH) on the short arm of chromosome 8 occurs at high frequencies in many tumor types, including colorectal carcinoma. We have previously used microcell‐mediated chromosome transfer (MMCT) to map an approximately 7.7 Mb colorectal cancer suppressor region (CRCSR)