✦ LIBER ✦

Gene amplification in mammalian cells: strategies for protein production

✍ Scribed by Rodney E. Kellems

Publisher: Elsevier Science
Year: 1991
Tongue: English
Weight: 643 KB
Volume: 2
Category: Article
ISSN: 0958-1669
DOI: 10.1016/0958-1669(91)90042-4

No coin nor oath required. For personal study only.

✦ Synopsis

Gene amplification is an experimental strategy for increasing protein production in mammalian cells. Co-amplification of the target gene by genetically linking it to one or more selectable and amplifiable genetic markers is a particularly successful strategy. A number of papers published in the past year or two illustrate the use of gene amplification to achieve high levels of expression.

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