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Gender specific differences in left ventricular remodelling in obesity may explain differences in obesity related mortality
β Scribed by Oliver J Rider; Adam J Lewandowski; Richard Nethononda; Steffen E Petersen; Alex Pitcher; Cameron Holloway; Rajarshi Banerjee; James P Byrne; Paul Leeson; Stefan Neubauer
- Publisher
- BioMed Central
- Year
- 2012
- Tongue
- English
- Weight
- 199 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1097-6647
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β¦ Synopsis
Across both genders, obesity, in the absence of traditional cardiovascular risk factors, is characterized by concentric LV remodeling. Whereas males show predominantly concentric remodeling, females exhibit eccentric and concentric hypertrophy. This may explain the observed gender difference in obesity related cardiovascular mortality.
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Background. Whether there are gender differences in the prognostic application of gated myocardial perfusion single photon emission computed tomography (SPECT) has not been assessed. Methods and Results. Gender-specific normal limits of poststress volume and ejection fraction (EF) were obtained in