Gender and genetic differences in bladder smooth muscle PPAR mRNA in a porcine model of the metabolic syndrome

Expression of RhoA mRNA and activated Rh

Expression of RhoA mRNA and activated RhoA in urothelium and smooth muscle, and effects of a rho-kinase inhibitor on contraction of the porcine urinary bladder

✍ Kimihiro Nakanishi; Takao Kamai; Tomoya Mizuno; Kyoko Arai; Tomonori Yamanishi 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 194 KB 👁 1 views

## Abstract ## Aims To investigate the concentration and activity of RhoA in detrusor and urothelium, as well as the effects of a Rho‐kinase inhibitor, Y‐27632 {(+)‐(R)‐trans‐4‐(1‐aminoethyl)‐N‐(4‐pyridyl) cyclohexanecarboxamide dihydrochloride}, on contraction of the pig urinary bladder. ## Meth