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Gemtuzumab ozogamicin for the treatment of acute promyelocytic leukemia: mechanisms of action and resistance, safety and efficacy

✍ Scribed by Breccia, Massimo; Lo-Coco, Francesco


Book ID
125475904
Publisher
Informa plc
Year
2010
Tongue
English
Weight
231 KB
Volume
11
Category
Article
ISSN
5847-4714

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Gemtuzumab ozogamicin in the treatment o
✍ Francis Giles; Elihu Estey; Susan O'Brien πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 484 KB πŸ‘ 2 views

## Abstract Gemtuzumab ozogamicin (GO) is a chemotherapeutic agent that consists of a humanized anti‐CD33 antibody (hP67.6) linked to N‐acetyl‐γ calicheamicin 1,2‐dimethyl hydrazine dichloride, a potent enediyne antitumor antibiotic. GO was approved conditionally by the Federal Drug Administration