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Geminally Difluorinated Pharmaceutical Agents: Synthesis and Applications

โœ Scribed by Jonathan M. Percy


Publisher
John Wiley and Sons
Year
2005
Weight
8 KB
Volume
36
Category
Article
ISSN
0931-7597

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Geminal Bis(sulfoximine)s: Synthesis and
โœ M. Reggelin; H. Weinberger; V. Spohr ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 418 KB ๐Ÿ‘ 2 views

## Abstract A number of __C__~2~โ€symmetrical geminal bis(sulfoximine)s have been prepared for the first time and used as ligands in boronโ€mediated reductions of acetophenone and copper complexโ€catalyzed 1,4โ€additions of diethylzinc to 2โ€cyclohexenone. The copper complex of bis(sulfoximine) 46 was f