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Gemcitabine chemoresistance and molecular markers associated with gemcitabine transport and metabolism in human pancreatic cancer cells

✍ Scribed by Nakano, Y; Tanno, S; Koizumi, K; Nishikawa, T; Nakamura, K; Minoguchi, M; Izawa, T; Mizukami, Y; Okumura, T; Kohgo, Y

Book ID
124167447
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
135 KB
Volume
96
Category
Article
ISSN
0007-0920

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## Abstract ## BACKGROUND: It has not been well established whether genetic variations can be biomarkers for clinical outcome of gemcitabine therapy. The purpose of this study was to identify single nucleotide polymorphisms (SNPs) of gemcitabine metabolic and transporter genes that are associated