✦ LIBER ✦
Gelation Rate Modulation of an α-Cyclodextrin and Poly(ethylene glycol)-Grafted Hyaluronic Acid Solution System by Inclusion Complexation of a Microphase-Separated Structure
✍ Scribed by Tsuyoshi Nakama; Tooru Ooya; Nobuhiko Yui
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 144 KB
- Volume
- 25
- Category
- Article
- ISSN
- 1022-1336
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✦ Synopsis
Abstract
Summary: The gelation rate of a poly(ethylene glycol)‐grafted hyaluronic acid (PEG‐graft‐HA) solution with adding α‐CD was investigated in term of the microphase separation between the grafted PEG and HA. The gelation rate of PEG‐graft‐HA exhibiting the microphase‐separated structure was two times higher than that of PEG‐graft‐HA showing a homogeneous miscible state.
The formation of microphases by PEG‐graft‐HA contributes to its rapid gelation upon the addition of α‐CDs.
imageThe formation of microphases by PEG‐graft‐HA contributes to its rapid gelation upon the addition of α‐CDs.