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Gelatinase Contributes to the Degradation of Glomerular Basement Membrane Collagen by Human Neutrophils

โœ Scribed by Margret C.M. Vissers; Christine C. Winterbourn


Book ID
114179110
Publisher
Elsevier
Year
1988
Weight
723 KB
Volume
8
Category
Article
ISSN
0174-173X

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Degradation of basement membrane collage
โœ S. E. Shields; D. J. Ogilvie; R. G. McKinnell; D. Tarin ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 438 KB

In this investigation it has been found that naturally-occurring (i.e. indigenous, not transplanted) tumours of diverse organs in a spectrum of vertebrates from frogs to man can secrete enzymes which degrade basement membrane collagens (type IV and V). The enzymes are inhibited by chelating agents (