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Gelatinase A expression in endothelial cells is regulated by at least two cis-acting promoter elements

✍ Scribed by Kurt D Bottles; Elizabeth C Bullen; Dawn L Updike; Thien-Khai H Vu; Eric Phelps; Paula Grammas; Eric W Howard

Book ID: 117481863
Publisher: Elsevier Science
Year: 1999
Tongue: English
Weight: 714 KB
Volume: 1428
Category: Article
ISSN: 0304-4165
DOI: 10.1016/s0304-4165(99)00059-8

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## Abstract Smooth muscle cells (SMC) play a central role in common vascular pathologies such as atherosclerosis and restenosis. Understanding the molecular regulation of SMC proliferation at a transcriptional level may provide important clues for the targeted control of vascular hyperplasia. We re