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Gee whiz: CpG DNA allergy therapy!

โœ Scribed by Askenase, Philip W.

Book ID
119764923
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
136 KB
Volume
106
Category
Article
ISSN
1097-6825

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Direct Immunologic activities of CpG DNA
Direct Immunologic activities of CpG DNA and implications for gene therapy
โœ Arthur M. Krieg ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 84 KB ๐Ÿ‘ 2 views

Vertebrate immune systems have evolved the ability to detect and be activated by most microbial and viral DNAs by virtue of their content of unmethylated `CpG motifs', which are selectively suppressed in vertebrate DNA. Because their CpGs are also unmethylated, the DNA in gene therapy vectors routin