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Gd-DOTA Conjugate of RGD as a Potential Tumor-Targeting MRI Contrast Agent

✍ Scribed by Ji-Ae Park; Jae-Jun Lee; Jae-Chang Jung; Dae-Yeul Yu; Chilhwan Oh; Seunghan Ha; Tae-Jeong Kim; Yongmin Chang


Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
307 KB
Volume
9
Category
Article
ISSN
1439-4227

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## Abstract The rationale and objectives were to define the MRI tumor‐characterizing potential of a new protein‐avid contrast agent, Gd‐GlyMe‐DOTA‐perfluorooctyl‐mannose‐conjugate (Gadofluorine M™; Schering AG, Berlin, Germany) in a chemically induced tumor model of varying malignancy. Because of t