We are researchers who have published analyses of nucleic acid sequence variation of hepatitis C virus (HCV) and associated virological and clinical significance. We are concerned that our investigations are hampered by the lack of a consensus nomenclature for variants of HCV and that this leads to
GBV-C/HGV genotypes: Proposed nomenclature for genotypes 1–5
✍ Scribed by Timothy J. Tucker; Heidi E. Smuts
- Book ID
- 101320131
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 118 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0146-6615
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GB virus C/hepatitis G virus (GBV-C/HGV) has been characterised as a novel flavivirus, and to date three known genotypes have been cloned. Greater genetic variation of GBV-C/HGV has been demonstrated in West African isolates, but no major deletions have been shown in the 5Ј non-coding region (NCR).
International standardization and coordination of the nomenclature of variants of hepatitis C virus (HCV) is increasingly needed as more is discovered about the scale of HCV-related liver disease and important biological and antigenic differences that exist between variants. A group of scientists ex