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Gating of Inward Rectifier K+ Channels by Proton-Mediated Interactions of Intracellular Protein Domains

✍ Scribed by Chun Jiang; Zhiqiang Qu; Haoxing Xu

Book ID
114342005
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
478 KB
Volume
12
Category
Article
ISSN
1050-1738

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## Abstract The mechanistic link between mitochondrial metabolism and inward rectifier K^+^ channel activity was investigated by studying the effects of a mitochondrial inhibitor, carbonyl cyanide p‐trifluoromethoxyphenylhydrazone (FCCP) on inward rectifiers of the K~ir~2 subfamily expressed in __X