Gating multiple signals through detailed balance of excitation and inhibition in spiking networks

Raloxifene induces cell death and inhibi

Raloxifene induces cell death and inhibits proliferation through multiple signaling pathways in prostate cancer cells expressing different levels of estrogen receptorα and β

✍ V. Rossi; G. Bellastella; C. De Rosa; C. Abbondanza; D. Visconti; L. Maione; P. 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 246 KB

## Abstract Raloxifene (RAL), a selective estrogen receptor (ER) modulator (SERM) seems to induce apoptosis in both androgen‐dependent and ‐independent prostate cell (PC) lines via activation of ERβ and an antagonistic effect on ERα. In this study, we evaluated the effects of RAL on epithelial PC g