The GATA-4/5/6 genes encode transcription factors implicated previously in the regulation of cardiac-specific differentiation programs. However, recent analyses of mouse GATA-4 null mutations found evidence for function in endoderm development (in vitro) and embryonic morphogenesis (in vivo). Whethe
β¦ LIBER β¦
GATA-4 regulates cardiac morphogenesis through transactivation of the N-cadherin gene
β Scribed by Hong Zhang; Toshihiko Toyofuku; Junko Kamei; Masatsugu Hori
- Book ID
- 116287523
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 412 KB
- Volume
- 312
- Category
- Article
- ISSN
- 0006-291X
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## Abstract Zinc (Zn) deficiency during pregnancy results in a wide variety of developmental abnormalities. The objective of this study was to determine if expression of cardiac developmental genes regulated by Znβfinger transcription factors could be modulated during dietary Zn deficiency. Rats we