Gastrointestinal lymphoma in Chinese: A retrospective analysis

✍ Scribed by R. Liang; D. Todd; T. K. Chan; R. P. Ng; F. C. S. Ho

• Publisher: John Wiley and Sons
• Year: 1987
• Tongue: English
• Weight: 631 KB
• Volume: 5
• Category: Article
• ISSN: 0278-0232
• DOI: 10.1002/hon.2900050206

✦ Synopsis

Eighty-four Chinese patients with gastrointestinal lymphoma were reviewed. There were 45 gastric and 39 intestinal lymphomas. The median age was 45 years and the male to female ratio 1.14: 1. Diffuse histiocytic (60 per cent) or diffuse large cell (53.5 per cent) lymphoma comprised a majority of the cases. A high incidence of gastrointestinal bleeding at presentation was observed in our patients. According to a modified staging classification, a larger proportion of patients with intestinal lymphoma had advanced disease (Stage 111 and IV) than those with gastric lymphoma (82 per Cent versus 55 per cent,p < 0.02) and gastric lymphoma carried a better prognosis. The modified staging classification used in this study appeared to stratify better the patients into 2 sub-groups of localized (Stage I and 11) and advanced (Stage 111 and IV) disease, which correlated very well with theprognosis. Good treatment results were obtained following intensive therapy in ourpatientswith localized disease (Stage I and 11). The poorer treatment results of patients with advanced disease (Stage 111 and IV) call for better chemotherapy regimens and earlier diagnosis. Surgical resection of the primary gastrointestinal lesion is recommended to prevent haemorrhage and perforation following chemotherapy, which occurred in 38 per cent of our patients whose gastrointestinal lesions were not resected.