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Gastrin-releasing peptide links stressor to cancer progression

✍ Scribed by Xinqiu Li; Yunfu Lv; Aihua Yuan; Zongfang Li

Book ID
106124234
Publisher
Springer-Verlag
Year
2010
Tongue
English
Weight
389 KB
Volume
136
Category
Article
ISSN
1432-1335

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## Abstract Epithelial cells lining the mature human colon do not normally express receptors for gastrin‐releasing peptide (GRPR). In contrast, we have shown that when aberrantly expressed in functional form in colon cancer, this protein acted as a morphogen where it caused tumor cells to adopt a b