𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Gastrin expression is regulated by the interplay of TGF-beta/smads and Wnt pathways

✍ Scribed by Lei, Shie; Chakladar, Abhijit; Wojtukiewicz, Lindsay J.; Wang, Timothy C.

Book ID
123120593
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
256 KB
Volume
124
Category
Article
ISSN
0016-5085

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Cloning and expression of a rat Smad1: R
Cloning and expression of a rat Smad1: Regulation by TGFß and modulation by the ras/MEK pathway
✍ Jianbo Yue; Melanie T. Hartsough; Randall S. Frey; Thomas Frielle; Kathleen M. M πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 230 KB

A new family of signaling intermediates for TGFß superfamily members and other growth factors has recently been identified and termed Smads. It has been suggested that the Smad1 subfamily is regulated primarily by the TGFß superfamily member bone morphogenetic protein (BMP). Here we demonstrate that

Expression of Smad4 in the FaDu cell lin
Expression of Smad4 in the FaDu cell line partially restores TGF-beta growth inhibition but is not sufficient to regulate fibronectin expression or suppress tumorigenicity
✍ B. Timothy Hummer; Christopher Bartlett; Erin Henry; Bernard E. Weissman πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 354 KB

## Abstract Mutations of the Smad4 gene, a member of a group of TGF‐β signal transduction components, occur in several types of cancer suggesting that its inactivation significantly affects TGF‐β responsiveness in these tumors. To further investigate the role of Smad4 with respect to TGF‐β signalin