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Gastric mucosal cell protection by epidermal growth factor in primary monolayer culture of guinea pig gastric mucous cells

โœ Scribed by Chikao Shimamoto; Ichiro Hirata; Eiji Umegaki; Hiroya Takiuchi; Yutaka Hiraike; Shoko Fujiwara; Ken-ichi Katsu


Publisher
Springer Japan
Year
2003
Tongue
English
Weight
274 KB
Volume
38
Category
Article
ISSN
0944-1174

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Epidermal growth factor (EGF) induced the disruption and scattering of colonies of TMK-1, a cell line derived from a human gastric carcinoma. A stimulatory action of EGF on cell migration was also observed as determined by a wound assay. However, these actions of EGF were inhibited if the cells were