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Gastric function and absorption of vitamin B12in children with celiac disease

✍ Scribed by J. Kokkonen; S. Similä

Book ID
104778240
Publisher
Springer
Year
1979
Tongue
English
Weight
283 KB
Volume
132
Category
Article
ISSN
0340-6997

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✦ Synopsis

Gastric acid secretion in nineteen children with celiac disease remained almost unchanged and the level of fasting serum gastrin was comparable with that of a control group of the same age. The absorption of vitamin Bl2 was significantly decreased, most clearly in the infants with celiac disease as compared with their controls. The serum B12 level, however, was decreased only in the oldest children. The results suggest that the mucosal lesion in the small intestine is most extensive in the youngest children, but the absorption defect of vitamin B12 becomes clinically significant only after a long duration of the disease and not in childhood.

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