Gastric Cancer

✍ Scribed by Carl J. Pfeiffer (auth.), Professor Dr. Christian H. Herfarth, Dr. Peter M. Schlag (eds.)

• Publisher: Springer-Verlag Berlin Heidelberg
• Year: 1979
• Tongue: English
• Leaves: 380
• Edition: 1
• Category: Library

✦ Synopsis

The problem of gastric cancer, with its multifaceted aspects, offers an example of diversified oncological research, which includes epidemiology, pathogenesis, histo­ morphology, surgical and conservative therapy in its spectrum. This disease not only constitutes an interesting and important subject for research, but it is also a challenge for the practitioner due to its inordinately poor prognosis. It therefore appeared a rewarding task to the editors to collect information from individual experts, in order to gain a topical summary of the problems pertaining to gastric cancer, as well as to provide a survey of the progress and the therapeutic possibilities in this field. This task was particularly enticing, as gastric cancer has lately come to belong to those tumors somewhat relegated to the shadows, although it is, despite its decreased fre­ quency in some western countries, still one of the most prevalent malignant diseases. This collection should emphasize the need for broadly based knowledge of individual problems as a prerequisite for any satisfactory therapy of an organ tumor. It is therefore the primary concern of this book to furnish anyone with an interest in oncology with this necessary survey. The editors thank Mrs. Karin Dohmeier and Mrs. Karin Kluge from Springer-Verlag for their cooperation in preparing this monograph. We extend our thanks to Mrs. Susanne Schenk and Mrs. Marga Wild, who contributed so much by her secretarial experience for the success of this volume. lJIm,September1979 Ch. Herfarth P. Schlag Table of Contents 1 Epidemiology and Pathogenesis . . . . . . . . . . .

✦ Table of Contents

Front Matter....Pages I-XV
Front Matter....Pages 1-1
Exogenous Factors in the Epidemiology of Gastric Carcinoma....Pages 2-8
Pathogenesis of Gastric Carcinoma: The Role of the Microenvironment....Pages 9-12
Carcinoma of the Stomach in Urbanized Black South Africans....Pages 13-14
Carcinogenic Substances and Carcinogenesis — Their Clinical Significance....Pages 15-18
Back Matter....Pages 19-19
Front Matter....Pages 21-21
Experimental Gastric Cancer: Pathogenesis and Clinico-Histopathologic Correlation....Pages 22-31
Epithelium at the Gastroenteral Borderline — Comparison of Animal Experiments and Clinical-Pathological Investigations....Pages 32-43
Experimental Cancer of the Gastric Stump....Pages 44-59
Formal Pathogenesis of Chemically-Induced Cancers After Gastric Operation....Pages 60-63
Vagotomy and Gastric Cancer....Pages 64-66
Susceptibility to Experimental Gastric Ulcer — Experimental Gastric Cancer, and Gastric Region....Pages 67-68
Back Matter....Pages 69-69
Front Matter....Pages 71-71
Histology of Possible Precancerous Stages in the Stomach....Pages 72-82
Dysplastic Changes in Intestinal Metaplasia of the Gastric Mucosa....Pages 83-90
Biological Significance of Dysplasias of the Epithelium and of Atrophic Gastritis....Pages 91-104
Significance and Location of Atrophic Gastritis and of Glandular Dysplasia in Benign and Malignant Gastric Disease....Pages 105-107
Endoscopic Therapy of Gastric Precancerosis....Pages 108-108
Back Matter....Pages 109-109
Front Matter....Pages 111-111
Duodenogastric Reflux and Epithelial Lesions....Pages 112-119
Nitrite and N -Nitrosocompounds in the Operated Stomach....Pages 120-128
Risk of Carcinoma in the Gastric Remnant After Gastric Resection for Benign Conditions....Pages 129-136
Remarks on Frequency and Pathogenesis of Primary Gastric Stump Cancer....Pages 137-144
Prospective Studies in Patients with Resected Stomach and Stump Carcinoma....Pages 145-146
Back Matter....Pages 149-149
Front Matter....Pages 111-111
Gastric Polyps and Gastric Cancer....Pages 147-148
Back Matter....Pages 149-149
Front Matter....Pages 151-151
Significance of Diagnostic Procedures for Preoperative Staging....Pages 152-156
Biological Markers for Staging of Gastric Cancer?....Pages 157-162
Typing, Grading, and Staging of Gastric Carcinoma....Pages 163-168
Back Matter....Pages 169-169
Front Matter....Pages 171-171
Cancer of the Stomach — Prognosis, Independent of Therapy....Pages 172-181
Prognostic Significance of Stromal Reaction in Gastric Carcinoma....Pages 182-186
A Statistical Trial on Evaluation for Prognosis of Gastric Cancer....Pages 187-192
Back Matter....Pages 193-193
Front Matter....Pages 195-195
Value of the Gastrectomy “ de Principe ”....Pages 196-204
On the Problem of “Stage-Appropriate” Treatment of Gastric Carcinoma....Pages 205-214
Local Excision — A Therapeutic Procedure in Early Gastric Carcinoma?....Pages 215-216
Influence of the Choice of Surgical Procedure in Gastric Cancer on the 5-Year Survival Time....Pages 217-219
Problems Associated with the Surgical Treatment of Cancer of the Gastric Stump....Pages 220-224
Back Matter....Pages 225-225
Front Matter....Pages 227-227
Pathophysiological Consequences of Total Gastrectomy....Pages 228-236
Importance of the Duodenal Passage Following Gastrectomy....Pages 237-241
Significance of the Duodenum for Carbohydrate Metabolism in Patients After Total Gastrectomy....Pages 242-247
Nutritional History in Gastrectomized Patients....Pages 248-249
Back Matter....Pages 250-250
Front Matter....Pages 251-251
Various Types of Reconstructive Methods After Gastrectomy....Pages 252-252
Esophagojejunostomy Following Gastrectomy for Gastric Carcinoma — A Follow-Up Study....Pages 253-256
Mortality and Morbidity After Esophagojejunostomy....Pages 257-259
Jejunal Interposition....Pages 260-265
Back Matter....Pages 318-318
Front Matter....Pages 251-251
Jejunal Interposition with Plication....Pages 266-271
Esophagojejunoplication....Pages 272-280
Comparative Analysis of Two Types of Gastric Replacement After Total Gastrectomy....Pages 281-286
The Jejunal Pouch as Stomach Substitute....Pages 287-292
Jejunal Pouch According to Hunt-Lawrence-Rodino with Jejunoplication....Pages 293-306
Jejunal Pouch After Total Gastrectomy: A Study of Different Substitutes for the Stomach....Pages 307-311
Quality of Life and Stomach Replacement....Pages 312-317
Back Matter....Pages 318-318
Front Matter....Pages 319-319
A Tentative Synopsis of the Nutritional Problems Encountered in Patients Afflicted with Malignant Neoplasia....Pages 320-326
Total Parenteral Nutrition in Regional Surgery for Gastric Cancer....Pages 327-338
Immunological Changes During a Perioperative Parenteral Hyperalimentation in Gastrointestinal Cancer....Pages 339-343
Results of Surgery for Gastric Cancer and Effect of Adjuvant Chemotherapy....Pages 344-356
A Controlled Prospective Study of Adjuvant 5-Fluorouracil and BCNU Therapy in Stomach Carcinoma....Pages 357-360
Chemotherapy in Advanced Gastric Cancer....Pages 361-366
Combination of Radio-Chemotherapy in Patients with Advanced Gastric Cancer....Pages 367-368
Back Matter....Pages 369-369
Back Matter....Pages 371-376

✦ Subjects

Medicine/Public Health, general