Gas phase ion–molecule reactions in a modified ion trap: H/D exchange of non-covalent complexes and coordinatively unsaturated platinum complexes

✍ Scribed by Gavin E. Reid; Richard A. J. O’Hair; Michelle L. Styles; W. David McFadyen; Richard J. Simpson

• Publisher: John Wiley and Sons
• Year: 1998
• Tongue: English
• Weight: 137 KB
• Volume: 12
• Category: Article
• ISSN: 0951-4198
• DOI: 10.1002/(sici)1097-0231(19981130)12:22<1701::aid-rcm392>3.0.co;2-s

✦ Synopsis

A commercially available electrospray ionization ion trap mass spectrometer has been modified to carry out gas phase ion-molecule reactions. The ability to study gas phase ion-molecule reactions in conjunction with collision induced dissociation (CID) based methods and the multistage trapping capabilities of the ion trap have been exploited in two ways: (i) gas phase H/D exchange reactions inside the ion trap, coupled with CID tandem mass spectrometry have been used to provide insights into the reactivity of non covalent complexes of amino acids and simple peptides, and (ii) CID prior to performing ion-molecule reactions has been used to synthesize and examine the reactivity of coordinatively unsaturated platinum complexes.