✦ LIBER ✦
Gas-chromatographic determination of 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea in plasma after reaction with trifluoroacetic anhydride
✍ Scribed by B. Caddy; O.R. Idowu
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 298 KB
- Volume
- 185
- Category
- Article
- ISSN
- 0003-2670
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✦ Synopsis
The reaction of 1-(2chloroethyl)-3-( t'rans-4-methylcyclohexyl)-1-nitrosourea (methyl-CCNU) with trifluoroacetic anhydride is reported. Gas-liquid chromatography of the resulting trifluoroacetyl derivative is applied to determine methyl-CCNU in plasma with a limit of detection of 1.5 pg ml-'.