Gap junctions in Drosophila: developmental expression of the entire innexin gene family
β Scribed by Lucy A Stebbings; Martin G Todman; Rose Phillips; Claire E Greer; Jennifer Tam; Pauline Phelan; Kirsten Jacobs; Jonathan P Bacon; Jane A Davies
- Book ID
- 118602394
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 569 KB
- Volume
- 113
- Category
- Article
- ISSN
- 0925-4773
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The Gja1 gene encoding the gap junction connexin 43 (Cx43) is dynamically regulated during limb morphogenesis. Transcript expression is found in many regions of the limb bud known to be important in regulating limb growth and patterning. In the newly emerged limb bud, Gja1 transcripts are first expr
Gap junctions are membrane channels that directly connect the cytoplasm of neighboring cells, allowing the exchange of ions and small molecules. Two analogous families of proteins, the connexins and innexins, are the channel-forming molecules in vertebrates and invertebrates, respectively. In order