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Gangliosides expressed on breast cancer cells are E-selectin ligands

✍ Scribed by Venktesh S. Shirure; Karissa A. Henson; Ronald L. Schnaar; Leonardo Nimrichter; Monica M. Burdick


Book ID
116301457
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
521 KB
Volume
406
Category
Article
ISSN
0006-291X

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## Abstract The metastatic breast cancer cell line, 4T1, abundantly expresses the oligosaccharide sialylated Lewis x (sLe^x^). SLe^x^ oligosaccharide on tumor cells can be recognized by E‐ and P‐selectin, contributing to tumor metastatic process. We observed that both selectins reacted with this ce