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Ganglioside therapy of type I diabetes: Enhancement of hyperglycemia in the low dose streptozotocin model

✍ Scribed by Jürgen Zielasek; Hubert Kolb


Book ID
118345408
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
233 KB
Volume
51
Category
Article
ISSN
0024-3205

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The low dose streptozotocin murine model
✍ H. Kromann; M. Christy; Å. Lernmark; M. Nedergaard; J. Nerup 📂 Article 📅 1982 🏛 Springer 🌐 English ⚖ 504 KB

The influence of sex on pancreatic islet B cell susceptibility to streptozotocin was studied in mice given multiple low doses of streptozotocin. Male C3 D2 F1 mice developed a steadily increasing blood glucose level after a lag period of about 3 weeks, in contrast to females who were resistant. Sple