Ganglioside GM3 and its biological functions
✍ Scribed by N. V. Prokazova; N. N. Samovilova; E. V. Gracheva; N. K. Golovanova
- Book ID
- 110155131
- Publisher
- Springer
- Year
- 2009
- Tongue
- English
- Weight
- 301 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0006-2979
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract The synthesis of sulfur‐linked GM~3~ epitope 2 is based on acid‐catalyzed and base‐promoted __S__‐glycosylation processes. As a precursor, 2‐__O__‐benzoyl‐3‐thiogalactoside 10 was required, and was obtained from 4,6‐__O__‐benzylidene‐galactoside 3 in six high‐yielding steps. Base‐promot
Glycosidation of the lactose derivative 4 with [1-13 C]-sialyl sialic acid gave the trisaccharide 5 which was transformed into [1c-13 C]-GM 3 ([1c-13 C]-1). xanthate 3, prepared from enzymatically obtained [1-13 C]-FULL PAPER Scheme 2 Reagents and conditions: (a) PST, AgOTf, CH 3 CN/CH 2 Cl 2 , Ϫ70°