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Ganglioside Alterations in the Central Nervous System of Rats Chronically Injected with Methylmalonic and Propionic Acids

✍ Scribed by V.M.T. Trindade; A.M. Brusque; J.R. Raasch; L.F. Pettenuzzo; H.P. Rocha; C.M.D. Wannmacher; M. Wajner


Book ID
110337094
Publisher
Springer
Year
2002
Tongue
English
Weight
319 KB
Volume
17
Category
Article
ISSN
0885-7490

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## Abstract A time‐course study was carried out to measure the acetylcholinesterase (AChE) gene expression in the brain of female rats exposed to different doses of sarin and physostigmine. Short‐term effects were studied with an acute single subcutaneous dose (s.c.) of 80Β Β΅gΒ kg^βˆ’1^ (0.5 Γ— LD~50~)