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Ganciclovir resistance and UL97 gene mutations in cytomegalovirus blood isolates from patients with AIDS treated with ganciclovir

✍ Scribed by Bruno Abraham; Stephane Lastere; Jacques Reynes; Frederic Bibollet-Ruche; Nicole Vidal; Michel Segondy


Book ID
117771603
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
81 KB
Volume
13
Category
Article
ISSN
1386-6532

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Five AIDS patients with cytomegalovirus (CMV) retinitis who had received ganciclovir (GCV) therapy were followed with serial blood sampling to detectchanges both in CMV load and in the genetic composition of genes UL97 and UL54 whilst receiving cidofovir (CDV) therapy. CDV neither reduced CMV load i