Zinc stimulates the production of toxic
β
Glenda M. Bishop; Ralf Dringen; Stephen R. Robinson
π
Article
π
2007
π
Elsevier Science
π
English
β 765 KB
The release of zinc (Zn) from glutamatergic synapses contributes to the neuropathology of ischemia, traumatic brain injury, and stroke. Astrocytes surround glutamatergic synapses and are vulnerable to the toxicity of Zn, which impairs their antioxidative glutathione (GSH) system and elevates the pro