Gamma probe location of 111 indium-labeled B72.3: An extension of immunoscintigraphy
✍ Scribed by Dr. David N. Krag; Michael K. Haseman; Patrick Ford; Lloyd Smith; Michael H. Taylor; Philip Schneider; James E. Goodnight
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 646 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0022-4790
No coin nor oath required. For personal study only.
✦ Synopsis
Eight colorectal and 5 ovarian cancer patients were evaluated with preoperative immunoscintigraphy and intraoperative gamma probe detection of tected the presence of tumor in every patient shown to have tumor at surgery. There was one false-positive scan. A total of 21 pathologically verified lesions were identified at surgery in the 1 1 patients with tumor. Immunoscintigraphy localized 12 (57%) and intraoperative gamma probe detection located 17 (8 I %) of the lesions. lntraoperative probe detection located 6 of 8 lesions smaller than 1 cm and 3 lesions that were not identified on initial surgical exploration. The gamma probe offers information that is complementary to immunoscintigraphy in that ( l ) it aids the surgeon in locating intra-and extra-abdominal lesions previously identified by immunoscintigraphy, (2) it locates lesions too small to be seen by immunoscintigraphy alone, ( 3 ) it locates lesions that otherwise might be missed at surgery, and (4) it provides objective evidence for adequacy of surgical resection of cancer in the abdominal cavity.