Ξ³-Hydroxybutyric acid is not a GABA-mime
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Ivan Osorio; Dr Robert A. Davidoff
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Article
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1979
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John Wiley and Sons
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English
β 607 KB
## Abstract Ξ³βHydroxybutyric acid (GHB), a pharmacologically active central nervous system constituent, has been postulated to function as a Ξ³βaminobtyric acid (GABA) agonist. This hypothesis was tested directly on GABAergic synapses in isolated, superfused frog spinal cord. Addition of GHB to the