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Gambogic acid is cytotoxic to cancer cells through inhibition of the ubiquitin-proteasome system

✍ Scribed by Felth, Jenny; Lesiak-Mieczkowska, Karolina; DâArcy, Padraig; Haglund, Caroline; Gullbo, Joachim; Larsson, Rolf; Linder, Stig; Bohlin, Lars; FryknÃ¤s, MÃ¥rten; Rickardson, Linda

Book ID: 120826488
Publisher: Springer US
Year: 2012
Tongue: English
Weight: 532 KB
Volume: 31
Category: Article
ISSN: 0167-6997
DOI: 10.1007/s10637-012-9902-y

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## Abstract Bowman–Birk inhibitors (BBI) from soybean and related proteins are naturally occurring protease inhibitors with potential health‐promoting properties within the gastrointestinal tract. In this work, we have investigated the effects of soybean BBI proteins on HT29 colon adenocarcinoma ce