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Gambogic acid enhances proteasome inhibitor-induced anticancer activity

✍ Scribed by Hongbiao Huang; Di Chen; Shujue Li; Xiaofen Li; Ningning Liu; Xiaoyu Lu; Shouting Liu; Kai Zhao; Canguo Zhao; Haiping Guo; Changshan Yang; Ping Zhou; Xiaoxian Dong; Change Zhang; Guanmei; Q. Ping Dou; Jinbao Liu

Book ID
116335580
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
821 KB
Volume
301
Category
Article
ISSN
0304-3835

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## Abstract As an oncoprotein, mutant p53 is a potential tumor‐specific target for cancer therapy. Most mutated forms of the protein are largely accumulated in cancer cells due to their increased stability. In the present study, we demonstrate that mutant p53 protein stability is regulated by gambo