Gallium(III) Iodide-catalyzed Biginelli-type Reaction Under Solvent-free Conditions: Efficient Synthesis of Dihydropyrimidine-2(1H)-one Derivatives
✍ Scribed by Dapeng Li; Haifeng Mao; Litao An; Zhihao Zhao; Prof. Dr. Jianping Zou
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 162 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0256-7660
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
The Biginelli‐type condensation of ethyl acetoacetate/cycloketone, aldehyde and urea/thiourea under solvent‐free condition catalyzed by 10% gallium(III) iodide to form dihydropyrimidine‐2(1__H__)‐one derivatives was described. This process offered one way to constructing dihydropyrimidine‐2(1__H__)‐ones in good to excellent yields with simple procedure and short reaction time.
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