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Gallium iodide/iodine as a versatile reagent for the aza-Prins cyclization: an expeditious synthesis of 4-iodopiperidines

✍ Scribed by J.S. Yadav; B.V. Subba Reddy; D.N. Chaya; G.G.K.S. Narayana Kumar; S. Aravind; A.C. Kunwar; C. Madavi


Book ID
104095179
Publisher
Elsevier Science
Year
2008
Tongue
French
Weight
198 KB
Volume
49
Category
Article
ISSN
0040-4039

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## Abstract The aza‐__Prins__ cyclization of homoallyl __N__‐tosylamine with aliphatic aldehydes gives __trans__‐2‐alkyl‐4‐iodo‐1‐tosylpiperidines. This method is chemoselective as it works only with the aliphatic aldehydes, and, in the case of aromatic aldehydes, the starting materials are recover