NF-ΞΊB inhibition triggers death of imati
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Nadia Lounnas; Catherine Frelin; Nadège Gonthier; Pascal Colosetti; Anne Sirvent
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Article
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2009
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John Wiley and Sons
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French
β 521 KB
## Abstract The BcrβAbl inhibitor imatinib is the current firstβline therapy for all newly diagnosed chronic myeloid leukemia (CML). Nevertheless, resistance to imatinib emerges as CML progresses to an acute deadly phase implying that physiopathologically relevant cellular targets should be validat