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Galactose transporters discriminate steric anomers at the cell surface in yeast

✍ Scribed by Toshio Fukasawa; Hiroshi Sakurai; Yasuhisa Nogi; Enrico Baruffini


Book ID
109295594
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
323 KB
Volume
9
Category
Article
ISSN
1567-1356

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## Abstract Mutations in the gene encoding ClC‐5 lead to X‐linked hypercalciuric nephrolithiasis (XLHN), characterized by proteinuria, hypercalciuria, and phosphaturia. In renal proximal tubule cells, ClC‐5 was identified as an important player in endocytosis, which ensures reabsorption of filtered