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Galactose Stabilizes Various Missense Mutants of α-Galactosidase in Fabry Disease

✍ Scribed by T. Okumiya; S. Ishii; T. Takenaka; R. Kase; S. Kamei; H. Sakuraba; Y. Suzuki


Book ID
115577337
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
294 KB
Volume
214
Category
Article
ISSN
0006-291X

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Residual activity of α-galactosidase A i
✍ Giovanni Romeo; Michele D'Urso; Alfredo Pisacane; Eric Blum; Antonio Falco; Anna 📂 Article 📅 1975 🏛 Springer 🌐 English ⚖ 602 KB

The alpha-galactosidase A activity from fibroblasts of five Fabry patients and five controls has been separated from alpha-galactosidase B through small DEAE-cellulose columns and in some experiments by treatment of the fibroblast extracts with Sepharose coupled to anti-alpha-galactosidase B antibod