## Abstract Various genomic alterations have been detected in glioblastoma. Chromosome 7p, with the epidermal growth factor receptor locus, together with chromosome 10q, with the phosphatase and tensin homologue deleted in chromosome 10 and deleted in malignant brain tumorsβ1 loci, and chromosome 9
Gain of chromosome 7 by chromogenic in
β Scribed by Beatriz A. Walter; Maria Begnami; Vladimir A. Valera; Mariarita Santi; Elisabeth J. Rushing; Martha Quezado
- Book ID
- 106481626
- Publisher
- Springer US
- Year
- 2010
- Tongue
- English
- Weight
- 676 KB
- Volume
- 101
- Category
- Article
- ISSN
- 0167-594X
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## Abstract The clinical course of astrocytoma grade 2 (A2) is highly variable and is not reflected by morphological characteristics. Earlier studies using small series of A2 cases suggest that in situ hybridization (ISH) with chromosomeβspecific DNA probes allows for frequent detection of aneusomy