Gadolinium-labeled liposomes containing amphiphilic Gd-DTPA derivatives of varying chain length: Targeted MRI contrast enhancement agents for the liver

Gadolinium-labeled liposomes containing

Gadolinium-labeled liposomes containing various amphiphilic Gd-DTPA derivatives: Targeted MRI contrast enhancement agents for the liver

✍ G. W. Kabalka; M. A. Davis; T. H. Moss; E. Buonocore; K. Hubner; E. Holmberg; K. 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 615 KB

Unique paramagnetic liposomal contrast agents were synthesized and utilized for selective augmentation of T1 MR imaging of the livers of normal Balb/c mice. A series of amphipathic gadolinium complexes, which mimic phospholipids, was incorporated into the lamella of small unilamellar liposomes such