Gadolinium-based contrast agents and nephrotoxicity
โ Scribed by Professor Sameh K. Morcos
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 26 KB
- Volume
- 68
- Category
- Article
- ISSN
- 1522-1946
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
## Abstract The biodistribution of approved gadolinium (Gd)โbased contrast agents (GBCAs) is reviewed. After intravenous injection GBCAs distribute in the blood and the extracellular space and transiently through the excretory organs. Preclinical animal studies and the available clinical literature
## Abstract Nephrogenic systemic fibrosis (NSF) is a potentially severe systemic disease typically characterized by fibrosis of the skin and connective tissues. The etiology of NSF is still unknown but is likely to be multifactorial. Specific triggers under scientific evaluation have included surge
We are grateful to Drs. Marzella, Blank, Gelperin, and Johann-Liang of the U.S. Food and Drug Administration for providing a timely update/reminder on the evolving safety concerns related to gadolinium and especially to Gadodiamide's association with nephrogenic systemic fibrosis (NSF) as well as th